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Adoptive therapy with redirected primary regulatory T cells results in antigen-specific suppression of arthritis

Regulatory T cells (Tregs) can suppress a wide range of immune cells, making them an ideal candidate for the treatment of autoimmunity. The potential clinical translation of targeted therapy with antigen-specific Tregs is hampered by the difficulties of isolating rare specificities from the natural...

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Detalhes bibliográficos
Main Authors: Wright, Graham P., Notley, Clare A., Xue, Shao-An, Bendle, Gavin M., Holler, Angelika, Schumacher, Ton N., Ehrenstein, Michael R., Stauss, Hans J.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2776462/
https://ncbi.nlm.nih.gov/pubmed/19884493
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0907396106
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