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Atomistic Simulations of the HIV-1 Protease Folding Inhibition
Biochemical experiments have recently revealed that the p-S8 peptide, with an amino-acid sequence identical to the conserved fragment 83–93 (S8) of the HIV-1 protease, can inhibit catalytic activity of the enzyme by interfering with protease folding and dimerization. In this study, we introduce a hi...
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| Главные авторы: | , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
The Biophysical Society
2008
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2440460/ https://ncbi.nlm.nih.gov/pubmed/18375506 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.107.127621 |
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