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Atomistic Simulations of the HIV-1 Protease Folding Inhibition

Biochemical experiments have recently revealed that the p-S8 peptide, with an amino-acid sequence identical to the conserved fragment 83–93 (S8) of the HIV-1 protease, can inhibit catalytic activity of the enzyme by interfering with protease folding and dimerization. In this study, we introduce a hi...

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Bibliografiset tiedot
Päätekijät: Verkhivker, Gennady, Tiana, Guido, Camilloni, Carlo, Provasi, Davide, Broglia, Ricardo A.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: The Biophysical Society 2008
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC2440460/
https://ncbi.nlm.nih.gov/pubmed/18375506
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.107.127621
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