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Insight into the Folding Inhibition of the HIV-1 Protease by a Small Peptide

It has recently been shown that the highly protected segments 24–34 (S(2)) and 83–93 (S(8)) of each of the two 99-mers of human immunodeficiency virus type 1 protease play an essential role in the folding of the monomers, giving rise to the so-called (postcritical) folding nucleus ((FN) minimum cond...

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Библиографические подробности
Главные авторы: Bonomi, Massimiliano, Gervasio, Francesco L., Tiana, Guido, Provasi, Davide, Broglia, Ricardo A., Parrinello, Michele
Формат: Artigo
Язык:Inglês
Опубликовано: Biophysical Society 2007
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC1989711/
https://ncbi.nlm.nih.gov/pubmed/17573430
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.107.106369
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