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Absence of Smad3 Induces Neutrophil Migration after Cutaneous Irradiation : Possible Contribution to Subsequent Radioprotection

Our previous work showed that 6 weeks after cutaneous irradiation, mice null (knockout, KO) for Smad3, a cytoplasmic downstream mediator of transforming growth factor-β, demonstrate less epidermal acanthosis and dermal inflammation than wild-type (WT) Smad3 mice. Analysis of the kinetics of inflamma...

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Главные авторы: Flanders, Kathleen C., Ho, Benjamin M., Arany, Praveen R., Stuelten, Christina, Mamura, Mizuko, Paterniti, Miya Okada, Sowers, Anastasia, Mitchell, James B., Roberts, Anita B.
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Investigative Pathology 2008
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2438286/
https://ncbi.nlm.nih.gov/pubmed/18502822
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2008.070937
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