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Mice Lacking Smad3 Are Protected Against Cutaneous Injury Induced by Ionizing Radiation

Transforming growth factor-β (TGF-β) plays a central role in the pathogenesis of inflammatory and fibrotic diseases, including radiation-induced fibrosis. We previously reported that mice null for Smad3, a key downstream mediator of TGF-β, show accelerated healing of cutaneous incisional wounds with...

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書誌詳細
主要な著者: Flanders, Kathleen C., Sullivan, Catherine D., Fujii, Makiko, Sowers, Anastasia, Anzano, Mario A., Arabshahi, Alidad, Major, Christopher, Deng, Chuxia, Russo, Angelo, Mitchell, James B., Roberts, Anita B.
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Investigative Pathology 2002
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC1867194/
https://ncbi.nlm.nih.gov/pubmed/11891202
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