Interference with Transforming Growth Factor-β/ Smad3 Signaling Results in Accelerated Healing of Wounds in Previously Irradiated Skin

Transforming growth factor (TGF)-β regulates many aspects of wound repair including inflammation, chemotaxis, and deposition of extracellular matrix. We previously showed that epithelialization of incisional wounds is accelerated in mice null for Smad3, a key cytoplasmic mediator of TGF-β signaling....

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Bibliografiske detaljer
Main Authors: Flanders, Kathleen C., Major, Christopher D., Arabshahi, Alidad, Aburime, Ekinadese E., Okada, Miya H., Fujii, Makiko, Blalock, Timothy D., Schultz, Gregory S., Sowers, Anastasia, Anzano, Mario A., Mitchell, James B., Russo, Angelo, Roberts, Anita B.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Investigative Pathology 2003
Fag:
Regular Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1892357/
https://ncbi.nlm.nih.gov/pubmed/14633599
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