Interference with Transforming Growth Factor-β/ Smad3 Signaling Results in Accelerated Healing of Wounds in Previously Irradiated Skin

Transforming growth factor (TGF)-β regulates many aspects of wound repair including inflammation, chemotaxis, and deposition of extracellular matrix. We previously showed that epithelialization of incisional wounds is accelerated in mice null for Smad3, a key cytoplasmic mediator of TGF-β signaling....

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: Flanders, Kathleen C., Major, Christopher D., Arabshahi, Alidad, Aburime, Ekinadese E., Okada, Miya H., Fujii, Makiko, Blalock, Timothy D., Schultz, Gregory S., Sowers, Anastasia, Anzano, Mario A., Mitchell, James B., Russo, Angelo, Roberts, Anita B.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Investigative Pathology 2003
Schlagworte:
Regular Articles
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1892357/
https://ncbi.nlm.nih.gov/pubmed/14633599
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!

Ähnliche Einträge