Smad3 Signaling Is Required for Epithelial-Mesenchymal Transition of Lens Epithelium after Injury

Lens epithelial cells undergo epithelial-mesenchymal transition (EMT) after injury as in cataract extraction, leading to fibrosis of the lens capsule. Fibrosis of the anterior capsule can be modeled in the mouse by capsular injury in the lens, which results in EMT of the lens epithelium and subseque...

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Detalhes bibliográficos
Main Authors: Saika, Shizuya, Kono-Saika, Satoko, Ohnishi, Yoshitaka, Sato, Misako, Muragaki, Yasuteru, Ooshima, Akira, Flanders, Kathleen C., Yoo, Jiyun, Anzano, Mario, Liu, Chia-Yang, Kao, Winston W.–Y., Roberts, Anita B.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Investigative Pathology 2004
Assuntos:
Regular Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1602265/
https://ncbi.nlm.nih.gov/pubmed/14742269
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