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Smad3 Signaling Is Required for Epithelial-Mesenchymal Transition of Lens Epithelium after Injury

Lens epithelial cells undergo epithelial-mesenchymal transition (EMT) after injury as in cataract extraction, leading to fibrosis of the lens capsule. Fibrosis of the anterior capsule can be modeled in the mouse by capsular injury in the lens, which results in EMT of the lens epithelium and subseque...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Saika, Shizuya, Kono-Saika, Satoko, Ohnishi, Yoshitaka, Sato, Misako, Muragaki, Yasuteru, Ooshima, Akira, Flanders, Kathleen C., Yoo, Jiyun, Anzano, Mario, Liu, Chia-Yang, Kao, Winston W.–Y., Roberts, Anita B.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Investigative Pathology 2004
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1602265/
https://ncbi.nlm.nih.gov/pubmed/14742269
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