Therapeutic Effect of Topical Administration of SN50, an Inhibitor of Nuclear Factor-κB, in Treatment of Corneal Alkali Burns in Mice

We evaluated the therapeutic efficacy of topical administration of SN50, an inhibitor of nuclear factor-κB, in a corneal alkali burn model in mice. An alkali burn was produced with 1 N NaOH in the cornea of C57BL/6 mice under general anesthesia. SN50 (10 μg/μl) or vehicle was topically administered...

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Detalhes bibliográficos
Main Authors: Saika, Shizuya, Miyamoto, Takeshi, Yamanaka, Osamu, Kato, Tadashi, Ohnishi, Yoshitaka, Flanders, Kathleen C., Ikeda, Kazuo, Nakajima, Yuji, Kao, Winston W.-Y., Sato, Misako, Muragaki, Yasuteru, Ooshima, Akira
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Investigative Pathology 2005
Assuntos:
Original Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1606394/
https://ncbi.nlm.nih.gov/pubmed/15855640
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