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Prediction of membrane-protein topology from first principles

The current best membrane-protein topology-prediction methods are typically based on sequence statistics and contain hundreds of parameters that are optimized on known topologies of membrane proteins. However, because the insertion of transmembrane helices into the membrane is the outcome of molecul...

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Detalhes bibliográficos
Main Authors: Bernsel, Andreas, Viklund, Håkan, Falk, Jenny, Lindahl, Erik, von Heijne, Gunnar, Elofsson, Arne
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2438223/
https://ncbi.nlm.nih.gov/pubmed/18477697
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0711151105
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