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Improved detection of homologous membrane proteins by inclusion of information from topology predictions

A total of 20%–25% of the proteins in a typical genome are helical membrane proteins. The transmembrane regions of these proteins have markedly different properties when compared with globular proteins. This presents a problem when homology search algorithms optimized for globular proteins are appli...

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Detalhes bibliográficos
Main Authors: Hedman, Maria, Deloof, Hans, Von Heijne, Gunnar, Elofsson, Arne
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2002
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2373465/
https://ncbi.nlm.nih.gov/pubmed/11847287
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