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Internal duplications in α-helical membrane protein topologies are common but the nonduplicated forms are rare

Many α-helical membrane proteins contain internal symmetries, indicating that they might have evolved through a gene duplication and fusion event. Here, we have characterized internal duplications among membrane proteins of known structure and in three complete genomes. We found that the majority of...

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Detalhes bibliográficos
Main Authors: Hennerdal, Aron, Falk, Jenny, Lindahl, Erik, Elofsson, Arne
Formato: Artigo
Idioma:Inglês
Publicado em: Wiley Subscription Services, Inc., A Wiley Company 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3009398/
https://ncbi.nlm.nih.gov/pubmed/20882639
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pro.510
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