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Internal duplications in α-helical membrane protein topologies are common but the nonduplicated forms are rare
Many α-helical membrane proteins contain internal symmetries, indicating that they might have evolved through a gene duplication and fusion event. Here, we have characterized internal duplications among membrane proteins of known structure and in three complete genomes. We found that the majority of...
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Main Authors: | , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Wiley Subscription Services, Inc., A Wiley Company
2010
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3009398/ https://ncbi.nlm.nih.gov/pubmed/20882639 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pro.510 |
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