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Best α-helical transmembrane protein topology predictions are achieved using hidden Markov models and evolutionary information

Methods that predict the topology of helical membrane proteins are standard tools when analyzing any proteome. Therefore, it is important to improve the performance of such methods. Here we introduce a novel method, PRODIV-TMHMM, which is a profile-based hidden Markov model (HMM) that also incorpora...

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Main Authors: Viklund, Håkan, Elofsson, Arne
格式: Artigo
語言:Inglês
出版: Cold Spring Harbor Laboratory Press 2004
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2279939/
https://ncbi.nlm.nih.gov/pubmed/15215532
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1110/ps.04625404
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