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Predicting the topology of transmembrane helical proteins using mean burial propensity and a hidden-Markov-model-based method
Helices in membrane spanning regions are more tightly packed than the helices in soluble proteins. Thus, we introduce a method that uses a simple scale of burial propensity and a new algorithm to predict transmembrane helical (TMH) segments and a positive-inside rule to predict amino-terminal orient...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Wiley-Blackwell
2003
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2323935/ https://ncbi.nlm.nih.gov/pubmed/12824500 |
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