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Predicting the topology of transmembrane helical proteins using mean burial propensity and a hidden-Markov-model-based method

Helices in membrane spanning regions are more tightly packed than the helices in soluble proteins. Thus, we introduce a method that uses a simple scale of burial propensity and a new algorithm to predict transmembrane helical (TMH) segments and a positive-inside rule to predict amino-terminal orient...

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Bibliografiske detaljer
Main Authors: Zhou, Hongyi, Zhou, Yaoqi
Format: Artigo
Sprog:Inglês
Udgivet: Wiley-Blackwell 2003
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2323935/
https://ncbi.nlm.nih.gov/pubmed/12824500
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