Prostaglandin E(2) glycerol ester, an endogenous COX-2 metabolite of 2-arachidonoylglycerol, induces hyperalgesia and modulates NFκB activity

BACKGROUND AND PURPOSE: Recombinant cyclooxygenase-2 (COX-2) oxygenates 2-arachidonoylglycerol (2-AG) in vitro. We examined whether prostaglandin E(2) glycerol ester (PGE(2)-G), a COX-2 metabolite of 2-AG, occurs endogenously and affects nociception and immune responses. EXPERIMENTAL APPROACH: Using...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Hu, S Shu-Jung, Bradshaw, H B, Chen, J S-C, Tan, B, Walker, J Michael
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2008
Assuntos:
Research Papers
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2437899/
https://ncbi.nlm.nih.gov/pubmed/18297109
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjp.2008.33
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados