15-Deoxy-Δ(12,14)-prostaglandin J(2)-Glycerol Ester, a Putative Metabolite of 2-Arachidonyl Glycerol, Activates Peroxisome Proliferator Activated Receptor γ

2-Arachidonyl glycerol (2-AG) is an endogenous arachidonic acid derivative capable of suppressing interleukin (IL)-2 production by activated T cells. 2-AG-mediated IL-2 suppression is dependent on cyclooxygenase-2 (COX-2) metabolism and peroxisome proliferator activated receptor γ (PPARγ) activation...

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Auteurs principaux: Raman, Priyadarshini, Kaplan, Barbara L. F., Thompson, Jerry T., Vanden Heuvel, John P., Kaminski, Norbert E.
Format: Artigo
Langue:Inglês
Publié: The American Society for Pharmacology and Experimental Therapeutics 2011
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Articles
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3127542/
https://ncbi.nlm.nih.gov/pubmed/21511917
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/mol.110.070441
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