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Effect of CCR5 receptor antagonists on endocytosis of the human CCR5 receptor in CHO-K1 cells
BACKGROUND AND PURPOSE: The CCR5 chemokine receptor is a member of the G protein-coupled receptor (GPCR) family that is expressed by macrophages, memory T-lymphocytes and dendritic cells and is activated by chemotactic proteins (e.g. MIP-1α [CCL3], MIP-1β [CCL4] and RANTES [CCL5]). CCR5 is also the...
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| Main Authors: | , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Nature Publishing Group
2008
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2437898/ https://ncbi.nlm.nih.gov/pubmed/18223665 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0707691 |
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