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Influence of receptor number on the stimulation by salmeterol of gene transcription in CHO-K1 cells transfected with the human β(2)-adrenoceptor

1. The β(2)-agonist salmeterol is a potent relaxant of airway smooth muscle with a long duration of action. Previous studies of cyclic AMP accumulation, however, have indicated that salmeterol is a low efficacy β(2)-agonist when compared to isoprenaline. Here we have compared the properties of salme...

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Détails bibliographiques
Auteurs principaux: McDonnell, J, Latif, M L, Rees, E S, Bevan, N J, Hill, S J
Format: Artigo
Langue:Inglês
Publié: 1998
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC1571039/
https://ncbi.nlm.nih.gov/pubmed/9831907
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0702139
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