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Salmeterol inhibition of mediator release from human lung mast cells by β-adrenoceptor-dependent and independent mechanisms

1. The long-acting β(2)-adrenoceptor agonist, salmeterol (10(−9)–10(−5) M), inhibited the IgE-mediated release of histamine from human lung mast cells (HLMC) in a dose-dependent fashion. Additional β-adrenoceptor agonists were studied and the rank order of potency for the inhibition of histamine rel...

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Detalhes bibliográficos
Main Authors: Chong, Lee K, Cooper, Elizabeth, Vardey, Christopher J, Peachell, Peter T
Formato: Artigo
Idioma:Inglês
Publicado em: 1998
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1565250/
https://ncbi.nlm.nih.gov/pubmed/9535032
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0701703
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