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Desensitisation of mast cell β(2)-adrenoceptor-mediated responses by salmeterol and formoterol
1. The long-acting β(2)-adrenoceptor agonist formoterol (10(−10)–10(−6) M) inhibited the IgE-dependent release of histamine from human lung mast cells in a concentration-dependent manner. Formoterol was more potent and a full agonist relative to the nonselective β-adrenoceptor agonist isoprenaline....
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2003
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1574181/ https://ncbi.nlm.nih.gov/pubmed/14662724 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0705599 |
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