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Desensitisation of mast cell β(2)-adrenoceptor-mediated responses by salmeterol and formoterol

1. The long-acting β(2)-adrenoceptor agonist formoterol (10(−10)–10(−6) M) inhibited the IgE-dependent release of histamine from human lung mast cells in a concentration-dependent manner. Formoterol was more potent and a full agonist relative to the nonselective β-adrenoceptor agonist isoprenaline....

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Detalhes bibliográficos
Main Authors: Scola, Anne-Marie, Chong, Lee K, Suvarna, S Kim, Chess-Williams, Russell, Peachell, Peter T
Formato: Artigo
Idioma:Inglês
Publicado em: 2003
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1574181/
https://ncbi.nlm.nih.gov/pubmed/14662724
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0705599
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