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Influence of receptor reserve on β-adrenoceptor-mediated responses in human lung mast cells
1. The effects of the β-adrenoceptor agonists isoprenaline and salbutamol on IgE-mediated histamine release from human lung mast cells (HLMC) were evaluated. Both agonists (10(−10)–10(−5) M) inhibited histamine release in a dose-dependent manner and isoprenaline (pD(2), 8.3±0.1, mean±s.e.mean) was m...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
1998
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1565451/ https://ncbi.nlm.nih.gov/pubmed/9690863 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0701897 |
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