Protection by dexamethasone of the functional desensitization to β(2)-adrenoceptor-mediated responses in human lung mast cells

1. The β-adrenoceptor agonist, isoprenaline, inhibited the IgE-mediated release of histamine from human lung mast cells (HLMC) in a dose-dependent manner. Maximal inhibitory effects were obtained with 0.1 μM isoprenaline. However, the inhibition of histamine release from HLMC by isoprenaline (0.1 μM...

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Hlavní autoři: Chong, Lee K, Drury, Duncan E J, Dummer, Jack F, Ghahramani, Parviz, Schleimer, Robert P, Peachell, Peter T
Médium: Artigo
Jazyk:Inglês
Vydáno: 1997
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Papers
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1564743/
https://ncbi.nlm.nih.gov/pubmed/9208139
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0701185
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