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Salmeterol-induced desensitization, internalization and phosphorylation of the human β(2)-adrenoceptor

1. Partial agonists of the β(2)-adrenoceptor which activate adenylyl cyclase are widely used as bronchodilators for the relief of bronchoconstriction accompanying many disease conditions, including bronchial asthma. The bronchodilator salmeterol has both a prolonged duration of action in bronchial t...

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Detalhes bibliográficos
Main Authors: January, Bridgette, Seibold, Anita, Allal, Chafika, Whaley, Brenda S, Knoll, Brian J, Moore, Robert H, Dickey, Burton F, Barber, Roger, Clark, Richard B
Formato: Artigo
Idioma:Inglês
Publicado em: 1998
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1565216/
https://ncbi.nlm.nih.gov/pubmed/9517390
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0701658
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