Differential phosphorylation and dephosphorylation of β(2)-adrenoceptor sites Ser262 and Ser355,356

1. Activated β(2)-adrenoceptors are rapidly desensitized by phosphorylation of Ser262 by protein kinase A (PKA) and of Ser355,356 by G-protein-coupled receptor kinase (GRK). We sought to determine whether the phosphorylation and subsequent dephosphorylation of these sites had similar kinetics and re...

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Autores principales: Iyer, Varsha, Tran, Tuan M, Foster, Estrella, Dai, Wenping, Clark, Richard B, Knoll, Brian J
Formato: Artigo
Lenguaje:Inglês
Publicado: Nature Publishing Group 2005
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Papers
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC1751300/
https://ncbi.nlm.nih.gov/pubmed/16331289
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0706551
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