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Effect of CCR5 receptor antagonists on endocytosis of the human CCR5 receptor in CHO-K1 cells

BACKGROUND AND PURPOSE: The CCR5 chemokine receptor is a member of the G protein-coupled receptor (GPCR) family that is expressed by macrophages, memory T-lymphocytes and dendritic cells and is activated by chemotactic proteins (e.g. MIP-1α [CCL3], MIP-1β [CCL4] and RANTES [CCL5]). CCR5 is also the...

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Detalhes bibliográficos
Main Authors: Longden, J, Cooke, E-L, Hill, S J
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2008
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2437898/
https://ncbi.nlm.nih.gov/pubmed/18223665
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0707691
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