Comparative pharmacology of recombinant human M(3) and M(5) muscarinic receptors expressed in CHO-K1 cells

1. Affinity estimates were obtained for several muscarinic antagonists against carbachol-stimulated [(3)H]-inositol phosphates accumulation in Chinese hamster ovary (CHO-K1) cells stably expressing either human muscarinic M(3) or M(5) receptor subtypes. The rationale for these studies was to generat...

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Detalhes bibliográficos
Main Authors: Watson, Nikki, Daniels, Donald V, Ford, Anthony P D W, Eglen, Richard M, Hegde, Sharath S
Formato: Artigo
Idioma:Inglês
Publicado em: 1999
Assuntos:
Papers
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1566024/
https://ncbi.nlm.nih.gov/pubmed/10385263
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0702551
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