Enhanced NK-cell development and function in BCAP-deficient mice

In B lymphocytes, the B-cell adaptor for phosphatidylinositol 3-kinase (BCAP) facilitates signaling from the antigen receptor. Mice lacking BCAP have a predominantly immature pool of B cells with impaired immune function and increased susceptibility to apoptosis. Unexpectedly, we have found that nat...

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Detaylı Bibliyografya
Asıl Yazarlar: MacFarlane, Alexander W., Yamazaki, Tetsuo, Fang, Min, Sigal, Luis J., Kurosaki, Tomohiro, Campbell, Kerry S.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society of Hematology 2008
Konular:
Immunobiology
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2435684/
https://ncbi.nlm.nih.gov/pubmed/18337558
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2007-08-107847
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