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Enhanced NK-cell development and function in BCAP-deficient mice
In B lymphocytes, the B-cell adaptor for phosphatidylinositol 3-kinase (BCAP) facilitates signaling from the antigen receptor. Mice lacking BCAP have a predominantly immature pool of B cells with impaired immune function and increased susceptibility to apoptosis. Unexpectedly, we have found that nat...
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| Autors principals: | , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
American Society of Hematology
2008
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2435684/ https://ncbi.nlm.nih.gov/pubmed/18337558 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2007-08-107847 |
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