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Pam (Protein associated with Myc) functions as an E3 Ubiquitin ligase and regulates TSC/mTOR signaling

The tumor suppressor tuberin, encoded by the Tuberous Sclerosis Complex (TSC) gene TSC2, negatively regulates the mammalian target of rapamycin (mTOR) pathway, which plays a key role in the control of cell growth and proliferation. In addition to naturally occurring mutations, several kinases includ...

詳細記述

保存先:
書誌詳細
主要な著者: Han, Sangyeul, Witt, Rochelle M., Santos, Túlio M., Polizzano, Carolyn, Sabatini, Bernardo L., Ramesh, Vijaya
フォーマット: Artigo
言語:Inglês
出版事項: 2008
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2435383/
https://ncbi.nlm.nih.gov/pubmed/18308511
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cellsig.2008.01.020
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