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Residue-Level Interrogation of Macromolecular Crowding Effects on Protein Stability
Theory predicts that macromolecular crowding affects protein behavior, but experimental confirmation is scant. Herein, we report the first residue-level interrogation of the effects of macromolecular crowding on protein stability. We observe up to a 100-fold increase in the stability, as measured by...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2008
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2435214/ https://ncbi.nlm.nih.gov/pubmed/18459780 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja8005995 |
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