Therapeutic vaccination with a trivalent T-cell receptor (TCR) peptide vaccine restores deficient FoxP3 expression and TCR recognition in subjects with multiple sclerosis

Therapeutic vaccination using T-cell receptor (TCR) peptides from V genes commonly expressed by potentially pathogenic T cells remains an approach of interest for treatment of multiple sclerosis (MS) and other autoimmune diseases. We developed a trivalent TCR vaccine containing complementarity deter...

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Main Authors: Vandenbark, Arthur A, Culbertson, Nicole E, Bartholomew, Richard M, Huan, Jianya, Agotsch, Marci, LaTocha, Dorian, Yadav, Vijayshree, Mass, Michele, Whitham, Ruth, Lovera, Jesus, Milano, June, Theofan, Georgia, Chou, Yuan K, Offner, Halina, Bourdette, Dennis N
格式: Artigo
語言:Inglês
出版: Blackwell Science Inc 2008
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Original Articles
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2433276/
https://ncbi.nlm.nih.gov/pubmed/17944900
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2567.2007.02703.x
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