Therapeutic vaccination with a trivalent T-cell receptor (TCR) peptide vaccine restores deficient FoxP3 expression and TCR recognition in subjects with multiple sclerosis

Therapeutic vaccination using T-cell receptor (TCR) peptides from V genes commonly expressed by potentially pathogenic T cells remains an approach of interest for treatment of multiple sclerosis (MS) and other autoimmune diseases. We developed a trivalent TCR vaccine containing complementarity deter...

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Detalhes bibliográficos
Main Authors: Vandenbark, Arthur A, Culbertson, Nicole E, Bartholomew, Richard M, Huan, Jianya, Agotsch, Marci, LaTocha, Dorian, Yadav, Vijayshree, Mass, Michele, Whitham, Ruth, Lovera, Jesus, Milano, June, Theofan, Georgia, Chou, Yuan K, Offner, Halina, Bourdette, Dennis N
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 2008
Assuntos:
Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2433276/
https://ncbi.nlm.nih.gov/pubmed/17944900
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2567.2007.02703.x
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