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The different effects of itraconazole on the pharmacokinetics of fexofenadine enantiomers
AIMS: The aim of this study was to determine the inhibitory effect of itraconazole, a P-glycoprotein (P-gp) inhibitor, on the stereoselective pharmacokinetics of fexofenadine. METHODS: A two-way double-blind, placebo-controlled crossover study was performed with a 2-week washout period. Twelve healt...
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| Autors principals: | , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Blackwell Science Inc
2008
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2432479/ https://ncbi.nlm.nih.gov/pubmed/18294330 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2125.2008.03116.x |
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