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Glucose Restriction Inhibits Skeletal Myoblast Differentiation by Activating SIRT1 through AMPK-Mediated Regulation of Nampt

It is intuitive to speculate that nutrient availability may influence differentiation of mammalian cells. Nonetheless, a comprehensive complement of the molecular determinants involved in this process has not been elucidated yet. Here, we have investigated how nutrients (glucose) affect skeletal myo...

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Detalhes bibliográficos
Main Authors: Fulco, Marcella, Cen, Yana, Zhao, Po, Hoffman, Eric P., McBurney, Michael W., Sauve, Anthony A., Sartorelli, Vittorio
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2431467/
https://ncbi.nlm.nih.gov/pubmed/18477450
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.devcel.2008.02.004
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