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Exercise alters SIRT1, SIRT6, NAD and NAMPT levels in skeletal muscle of aged rats

Silent information regulators are potent NAD(+)-dependent protein deacetylases, which have been shown to regulate gene silencing, muscle differentiation and DNA damage repair. Here, changes in the level and activity of sirtuin 1 (SIRT1) in response to exercise in groups of young and old rats were st...

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Detalhes bibliográficos
Main Authors: Koltai, Erika, Szabo, Zsofia, Atalay, Mustafa, Boldogh, Istvan, Naito, Hisashi, Goto, Sataro, Nyakas, Csaba, Radak, Zsolt
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2872991/
https://ncbi.nlm.nih.gov/pubmed/19913571
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mad.2009.11.002
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