Hepatitis C Virus NS3 Helicase Forms Oligomeric Structures That Exhibit Optimal DNA Unwinding Activity in Vitro

HCV NS3 helicase exhibits activity toward DNA and RNA substrates. The DNA helicase activity of NS3 has been proposed to be optimal when multiple NS3 molecules are bound to the same substrate molecule. NS3 catalyzes little or no measurable DNA unwinding under single cycle conditions in which the conc...

Celý popis

Uloženo v:
Podrobná bibliografie
Hlavní autoři: Sikora, Bartek, Chen, Yingfeng, Lichti, Cheryl F., Harrison, Melody K., Jennings, Thomas A., Tang, Yong, Tackett, Alan J., Jordan, John B., Sakon, Joshua, Cameron, Craig E., Raney, Kevin D.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2008
Témata:
Enzyme Catalysis and Regulation
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2431078/
https://ncbi.nlm.nih.gov/pubmed/18283103
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M708125200
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky