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The Tec Family Tyrosine Kinase Btk Regulates RANKL-induced Osteoclast Maturation
A spontaneous mutation in Bruton's tyrosine kinase (Btk) induces a defect in B-cell development that results in the immunodeficiency diseases X-linked agammaglobulinemia in humans and X-linked immunodeficiency (Xid) in mice. Here we show an unexpected role of Btk in osteoclast formation. When b...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
American Society for Biochemistry and Molecular Biology
2008
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2431049/ https://ncbi.nlm.nih.gov/pubmed/18281276 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M708935200 |
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