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Identification of LRRc17 as a Negative Regulator of Receptor Activator of NF-κB Ligand (RANKL)-induced Osteoclast Differentiation

Osteoblasts are the primary cells responsible for bone formation. They also support osteoclast formation from bone marrow precursors in response to osteotropic factors by inducing receptor activator of NF-κB ligand (RANKL) expression and down-regulating osteoprotegerin (OPG) production. In addition...

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Detalhes bibliográficos
Main Authors: Kim, Taesoo, Kim, Kabsun, Lee, Seoung Hoon, So, Hong-Seob, Lee, Junwon, Kim, Nacksung, Choi, Yongwon
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2685711/
https://ncbi.nlm.nih.gov/pubmed/19336404
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M807722200
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