Identification of LRRc17 as a Negative Regulator of Receptor Activator of NF-κB Ligand (RANKL)-induced Osteoclast Differentiation

Osteoblasts are the primary cells responsible for bone formation. They also support osteoclast formation from bone marrow precursors in response to osteotropic factors by inducing receptor activator of NF-κB ligand (RANKL) expression and down-regulating osteoprotegerin (OPG) production. In addition...

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Bibliographische Detailangaben
Hauptverfasser: Kim, Taesoo, Kim, Kabsun, Lee, Seoung Hoon, So, Hong-Seob, Lee, Junwon, Kim, Nacksung, Choi, Yongwon
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Biochemistry and Molecular Biology 2009
Schlagworte:
Molecular Basis of Cell and Developmental Biology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2685711/
https://ncbi.nlm.nih.gov/pubmed/19336404
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M807722200
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