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Phosphoinositide Binding to the Substrate Regulates Susceptibility to Proteolysis by Calpain
Calpain-mediated proteolysis regulates cytoskeletal dynamics and is altered during aging and the progression of numerous diseases or pathological conditions. Although several cytoskeletal proteins have been identified as substrates, how localized calpain activity is regulated and the mechanisms cont...
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| Autors principals: | , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
American Society for Biochemistry and Molecular Biology
2008
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2431029/ https://ncbi.nlm.nih.gov/pubmed/18258589 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M707436200 |
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