An Internal Signal Sequence Directs Intramembrane Proteolysis of a Cellular Immunoglobulin Domain Protein

Precursor proteolysis is a crucial mechanism for regulating protein structure and function. Signal peptidase (SP) is an enzyme with a well defined role in cleaving N-terminal signal sequences but no demonstrated function in the proteolysis of cellular precursor proteins. We provide evidence that SP...

Full description

Saved in:
Bibliographic Details
Main Authors: Robakis, Thalia, Bak, Beata, Lin, Shu-huei, Bernard, Daniel J., Scheiffele, Peter
Format: Artigo
Language:Inglês
Published: American Society for Biochemistry and Molecular Biology 2008
Subjects:
Protein Synthesis, Post-Translational Modification, and Degradation
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2662301/
https://ncbi.nlm.nih.gov/pubmed/18981173
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M807527200
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items