An Internal Signal Sequence Directs Intramembrane Proteolysis of a Cellular Immunoglobulin Domain Protein

Precursor proteolysis is a crucial mechanism for regulating protein structure and function. Signal peptidase (SP) is an enzyme with a well defined role in cleaving N-terminal signal sequences but no demonstrated function in the proteolysis of cellular precursor proteins. We provide evidence that SP...

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Detaylı Bibliyografya
Asıl Yazarlar: Robakis, Thalia, Bak, Beata, Lin, Shu-huei, Bernard, Daniel J., Scheiffele, Peter
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Biochemistry and Molecular Biology 2008
Konular:
Protein Synthesis, Post-Translational Modification, and Degradation
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2662301/
https://ncbi.nlm.nih.gov/pubmed/18981173
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M807527200
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