Ubiquitylation on Canonical and Non-canonical Sites Targets the Transcription Factor Neurogenin for Ubiquitin-mediated Proteolysis

Polyubiquitylation targets multiple proteins for degradation by the proteasome. Typically, the first ubiquitin is linked to lysine residues in the substrate for degradation via an isopeptide bond, although rarely ubiquitin linkage to the N-terminal residue has also been observed. We have recently sh...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Κύριοι συγγραφείς: Vosper, Jonathan M. D., McDowell, Gary S., Hindley, Christopher J., Fiore-Heriche, Christelle S., Kucerova, Romana, Horan, Ian, Philpott, Anna
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: American Society for Biochemistry and Molecular Biology 2009
Θέματα:
Protein Synthesis, Post-Translational Modification, and Degradation
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2708843/
https://ncbi.nlm.nih.gov/pubmed/19336407
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M809366200
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