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Cell cycle-regulated multi-site phosphorylation of Neurogenin 2 coordinates cell cycling with differentiation during neurogenesis

During development of the central nervous system, the transition from progenitor maintenance to differentiation is directly triggered by a lengthening of the cell cycle that occurs as development progresses. However, the mechanistic basis of this regulation is unknown. The proneural transcription fa...

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Bibliografiske detaljer
Main Authors: Ali, Fahad, Hindley, Chris, McDowell, Gary, Deibler, Richard, Jones, Alison, Kirschner, Marc, Guillemot, Francois, Philpott, Anna
Format: Artigo
Sprog:Inglês
Udgivet: Company of Biologists 2011
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3171226/
https://ncbi.nlm.nih.gov/pubmed/21852393
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.067900
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