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Choline deficiency increases lymphocyte apoptosis and DNA damage in humans,

BACKGROUND: Whereas deficiency of the essential nutrient choline is associated with DNA damage and apoptosis in cell and rodent models, it has not been shown in humans. OBJECTIVE: The objective was to ascertain whether lymphocytes from choline-deficient humans had greater DNA damage and apoptosis th...

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Detalhes bibliográficos
Principais autores: da Costa, Kerry-Ann, Niculescu, Mihai D, Craciunescu, Corneliu N, Fischer, Leslie M, Zeisel, Steven H
Formato: Artigo
Idioma:Inglês
Publicado em: 2006
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2430662/
https://ncbi.nlm.nih.gov/pubmed/16825685
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