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Lymphocyte gene expression in subjects fed a low-choline diet differs between those who develop organ dysfunction and those who do not

BACKGROUND: Some humans fed a low-choline diet develop hepatosteatosis, liver and muscle damage, and lymphocyte apoptosis. The risk of developing such organ dysfunction is increased by the presence of single-nucleotide polymorphisms (SNPs) in genes involved in folate and choline metabolism. OBJECTIV...

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Detalhes bibliográficos
Main Authors: Niculescu, Mihai D, da Costa, Kerry-Ann, Fischer, Leslie M, Zeisel, Steven H
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2587282/
https://ncbi.nlm.nih.gov/pubmed/17616785
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