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Regulation of Choline Deficiency Apoptosis by Epidermal Growth Factor in CWSV-1 Rat Hepatocytes

Previous studies show that acute choline deficiency (CD) triggers apoptosis in cultured rat hepatocytes (CWSV-1 cells). We demonstrate that prolonged EGF stimulation (10 ng/mL x 48 hrs) restores cell proliferation, as assessed by BrdU labeling, and protects cells from CD-induced apoptosis, as assess...

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Detalhes bibliográficos
Main Authors: Albright, Craig D., Costa, Kerry-Ann da, Craciunescu, Corneliu N., Klem, Erich, Mar, Mei-Heng, Zeisel, Steven H.
Formato: Artigo
Idioma:Inglês
Publicado em: 2005
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2424026/
https://ncbi.nlm.nih.gov/pubmed/15665516
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000083653
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