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Choline deficiency alters global histone methylation and epigenetic marking at the Re1 site of the calbindin 1 gene
Maternal choline availability is essential for fetal neurogenesis. Choline deprivation (CD) causes hypomethylation of specific CpG islands in genes controlling cell cycling in fetal hippocampus. We now report that, in C57BL/6 mice, CD during gestational days 12–17 also altered methylation of the his...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Federation of American Societies for Experimental Biology
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2797040/ https://ncbi.nlm.nih.gov/pubmed/19752176 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.09-140145 |
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