Cigarette smoke–induced neurogenic inflammation is mediated by α,β-unsaturated aldehydes and the TRPA1 receptor in rodents

Cigarette smoke (CS) inhalation causes an early inflammatory response in rodent airways by stimulating capsaicin-sensitive sensory neurons that express transient receptor potential cation channel, subfamily V, member 1 (TRPV1) through an unknown mechanism that does not involve TRPV1. We hypothesized...

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Main Authors: Andrè, Eunice, Campi, Barbara, Materazzi, Serena, Trevisani, Marcello, Amadesi, Silvia, Massi, Daniela, Creminon, Christophe, Vaksman, Natalya, Nassini, Romina, Civelli, Maurizio, Baraldi, Pier Giovanni, Poole, Daniel P., Bunnett, Nigel W., Geppetti, Pierangelo, Patacchini, Riccardo
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Clinical Investigation 2008
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2430498/
https://ncbi.nlm.nih.gov/pubmed/18568077
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI34886
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